LEMS Overview
Referenced Journal Articles
TThe LEMS Family Association was incorporated in Texas on June 14, 2022. It began with the vision of a small group of passionate LEMS patients and continues to grow through the dedication of volunteers—especially our board of directors—who give their time, energy, and lived experience to support the community.
- Varon MC, Dimachkie MM. Diagnosis and treatment of Lambert-Eaton myasthenic syndrome. Practical Neurology (US). 2024;23(3):26-28,47.
- Zalewski NL, Lennon VA, Lachance DH, Klein CJ, Pittock SJ, Mckeon A. P/Q and N-type calcium-channel antibodies: Oncological, neurological, and serological accompaniments. Muscle Nerve. 2016 Aug;54(2):220-7. doi: 10.1002/mus.25027. Epub 2016 Feb 8. PMID: 26789908; PMCID: PMC4940238.
- Preßler, H., Haddy, I., Daugherty, C. et al. Paraneoplastic Lambert–Eaton myasthenic syndrome associated with non-small cell lung cancer: data from the European LEMS registry and systematic review. Neurol. Res. Pract. 7, 95 (2025).
- Titulaer MJ, Soffietti R, Dalmau J, Gilhus NE, Giometto B, Graus F, Grisold W, Honnorat J, Sillevis Smitt PA, Tanasescu R, Vedeler CA, Voltz R, Verschuuren JJ; European Federation of Neurological Societies. Screening for tumours in paraneoplastic syndromes: report of an EFNS task force. Eur J Neurol. 2011 Jan;18(1):19-e3. doi: 10.1111/j.1468-1331.2010.03220.x. Epub 2010 Sep 29. PMID: 20880069; PMCID: PMC3086523.
- Wirtz PW, Verschuuren JJ, van Dijk JG, de Kam ML, Schoemaker RC, van Hasselt JG, Titulaer MJ, Tjaden UR, den Hartigh J, van Gerven JM. Efficacy of 3,4- diaminopyridine and pyridostigmine in the treatment of Lambert-Eaton myasthenic syndrome: a randomized, double-blind, placebo-controlled, crossover study. Clin Pharmacol Ther. 2009 Jul;86(1):44-8. doi: 10.1038/clpt.2009.35. Epub 2009 Apr 8. PMID: 19357643.
- Tavee J, Brannagan TH 3rd, Lenihan MW, Muppidi S, Kellermeyer L, D Donofrio P; AANEM. Updated consensus statement: Intravenous immunoglobulin in the treatment of neuromuscular disorders report of the AANEM ad hoc committee. Muscle Nerve. 2023 Oct;68(4):356-374. doi: 10.1002/mus.27922. Epub 2023 Jul 11. PMID: 37432872.
- Park SK, Taylor MG. A Unique Case of Non-paraneoplastic Lambert-Eaton Myasthenic Syndrome Treated With Subcutaneous Immunoglobulin: A Case Report and Review of Literature. Cureus. 2024 May 21;16(5):e60773. doi: 10.7759/cureus.60773. PMID: 38903354; PMCID: PMC11188003.
- Yuste Ara JR, Beloqui Ruiz O, Artieda Gonzalez-Granda J, Herrero Santos JI, De la Peña Fernandez A, Prieto Valtueña J. Ciclosporina-A como tratamiento del síndrome miasteniforme de Eaton-Lambert [Cyclosporin A in the treatment of Eaton-Lambert myasthenic syndrome]. An Med Interna. 1996 Jan;13(1):25-6. Spanish. PMID: 8679819.
- Hussein G, Liu B, Yadav SK, Warsame M, Jamil R, Surani SR, Khan SA. Plasmapheresis in the ICU. Medicina. 2023; 59(12):2152.
- Vatkar A, Kale S, Shyam A, Srivastava S. Understanding the Levels of Evidence in Medical Research. J Orthop Case Rep. 2025 May;15(5):6-9. doi: 10.13107/jocr.2025.v15.i05.5534. PMID: 40351623; PMCID: PMC12064251.
- Xiangxiang W, Mengjiao S, Shoumei J, Kaitao Y, Yafang X, Jie J. Rehabilitation for functional enhancement of myasthenia gravis: A systematic review and meta analysis. eNeurologicalSci. 2025 Oct 9;41:100591. doi: 10.1016/j.ensci.2025.100591. PMID: 41142446; PMCID: PMC12547834.
- Huda R. Inflammation and autoimmune myasthenia gravis. Front Immunol. 2023 Jan 30;14:1110499. doi: 10.3389/fimmu.2023.1110499. PMID: 36793733; PMCID: PMC9923104.
- Furman D, Campisi J, Verdin E, Carrera-Bastos P, Targ S, Franceschi C, Ferrucci L, Gilroy DW, Fasano A, Miller GW, Miller AH, Mantovani A, Weyand CM, Barzilai N, Goronzy JJ, Rando TA, Effros RB, Lucia A, Kleinstreuer N, Slavich GM. Chronic inflammation in the etiology of disease across the life span. Nat Med. 2019 Dec;25(12):1822-1832. doi: 10.1038/s41591-019-0675-0. Epub 2019 Dec 5. PMID: 31806905; PMCID: PMC7147972.
- Yu X, Pu H, Voss M. Overview of anti-inflammatory diets and their promising effects on non-communicable diseases. Br J Nutr. 2024 Oct 14;132(7):898-918. doi: 10.1017/S0007114524001405. Epub 2024 Oct 16. PMID: 39411832; PMCID: PMC11576095.
- Pardali EC, Gkouvi A, Gkouskou KK, Manolakis AC, Tsigalou C, Goulis DG, Bogdanos DP, Grammatikopoulou MG. Autoimmune protocol diet: A personalized elimination diet for patients with autoimmune diseases. Metabol Open. 2024 Dec 30;25:100342. doi: 10.1016/j.metop.2024.100342. PMID: 39850611; PMCID: PMC11755016.
- Lehnerer S, Herdick M, Stegherr R, Gerischer L, Stascheit F, Stein M, Mergenthaler P, Hoffmann S, Meisel A. Burden of disease in Lambert-Eaton myasthenic syndrome: taking the patient’s perspective. J Neurol. 2024 May;271(5):2824-2839. doi: 10.1007/s00415-024-12206-6. Epub 2024 Feb 29. PMID: 38421419; PMCID: PMC11055781.